Mondo Description Any orofacial cleft in which the cause of the disease is a mutation in the BMP4 gene.

Uniprot Description A birth defect consisting of cleft lips with or without cleft palate. Cleft lips are associated with cleft palate in two-third of cases. A cleft lip can occur on one or both sides and range in severity from a simple notch in the upper lip to a complete opening in the lip extending into the floor of the nostril and involving the upper gum.