Mondo Description A broad classification of inherited disorders presenting at birth that affect both the cell-mediated and humoral aspects of the immune response. Circulating numbers of B lymphocytes, T lymphocytes and NK cells are variable but where present do not function properly. Susceptibility to infection is the primary concern.

Disease Ontology Description A primary immunodeficiency disease that involves multiple components of the immune system, including both humoral immunity and cell-mediated immunity.