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vitiligo
Disease Summary
Associated Targets (322)
Tbio
177
Tdark
85
Tchem
45
Tclin
15
Mondo Description Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes.
Uniprot Description A pigmentary disorder of the skin and mucous membranes. It is characterized by circumscribed depigmented macules and patches, commonly on extensor aspects of extremities, on the face or neck and in skin folds. Vitiligo is a progressive disorder in which some or all of the melanocytes in the affected skin are selectively destroyed. It is a multifactorial disorder with a complex etiology probably including autoimmune mechanisms, and is associated with an elevated risk of other autoimmune diseases.
Disease Ontology Description An autoimmune hypersensitivity disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
Description from UniProt.
Description from Disease Ontology
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
COHD:138502
DOID:12306
EFO:0004208
ICD10:L80
MESH:D014820
NCIT:C26915
OMIM:193200
UMLS:C0042900
MONDO:0008661
High level summary of knowledge for a disease, including descriptions and datasource references.