You are using an outdated browser. Please upgrade your browser to improve your experience.

systemic sclerosis

Disease Summary
Associated Targets (253)
Tbio

179

Tchem

36

Tdark

27

Tclin

11


GARD Rare
Mondo Description A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The two types of systemic scleroderma, limited cutaneous and diffuse cutaneous are classified with focus on the extent of affected skin. A relationship exists between the extent of skin area affected and degree of internal organ/system involvement. Systemic scleroderma can manifest itself in pulmonary fibrosis, Raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension.
Disease Ontology Description A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
Mondo Term and Equivalent IDs
MONDO:0005100:  systemic sclerosis
COHD:134442: 
EFO:0000717: 
GARD:0009748: 
ICD9:710.1: 
MESH:D012595: 
NCIT:C72070: 
Orphanet:90291: 
SCTID:89155008: 
UMLS:CN206012: