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pneumocystosis

Disease Summary
Associated Targets (10)
Tchem

8

Tclin

2


GARD Rare
Mondo Description Human pneumocystosis is caused by an infectious agent, which (after recent nomenclature and taxonomy revisions) is now classed as the fungus Pneumocystis jiroveci. The prevalence is unknown. Pneumocystis jiroveci is an opportunistic infectious agent, developing in immunosuppressed patients. It is an air-borne infection, localised to the lungs. However, extrapulmonary involvement is seen in AIDS patients. The disease manifests progressively with coughing, respiratory problems (dyspnea) and fever, followed by acute respiratory insufficiency and death within a few weeks in untreated cases. The most reliable diagnostic method is bronchoalveolar lavage. The treatment of choice is cotrimoxazole.
Disease Ontology Description An opportunistic mycosis that is located in lungs, but can also occur in eyes, ears, skin, thyroid, pituitary, palate, parathyroid, esophagus, pleura, heart, liver, spleen, small intestine, adrenals, kidneys, bone marrow, and lymph nodes, has material basis in Pneumocystis jirovecii that effects interstitial and alveolar tissues and has symptom nonproductive cough, has symptom shortness of breath, and has symptom fever.
Mondo Term and Equivalent IDs
MONDO:0019121:  pneumocystosis
COHD:438350: 
EFO:0007448: 
GARD:0004386: 
ICD10:B59: 
MESH:D011020: 
NCIT:C3334: 
Orphanet:723: 
SCTID:415125002: 
UMLS:C1535939: