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immunoglobulin-mediated membranoproliferative glomerulonephritis

Disease Summary
Associated Targets (2)
Tbio

2


Mondo Description Glomerulonephritis characterized by mesangial proliferation, endocapillary proliferation, and glomerular capillary wall remodeling with immune complex deposits from classical complement pathway activation.
Uniprot Description An atypical form of hemolytic uremic syndrome characterized by acute onset in the first year of life of microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. After the acute episode, most patients develop chronic renal insufficiency. Unlike other genetic forms of aHUS, AHUS7 is not related to abnormal activation of the complement system.
Mondo Term and Equivalent IDs
MONDO:0014005:  immunoglobulin-mediated membranoproliferative glomerulonephritis
NCIT:C123055: 
Orphanet:329903: