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systemic lupus erythematosus, susceptibility to, 10
Disease Summary
Associated Targets (1)
Tbio
1
Mondo Description Any systemic lupus erythematosus in which the cause of the disease is a mutation in the IRF5 gene.
Uniprot Description A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Mondo Term and Equivalent IDs
MONDO:0012834: systemic lupus erythematosus, susceptibility to, 10
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Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
Description from UniProt.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
OMIM:612251
MONDO:0012834
High level summary of knowledge for a disease, including descriptions and datasource references.