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granular corneal dystrophy type II

Disease Summary
Associated Targets (1)
Tbio

1


GARD Rare
Mondo Description Type II granular corneal dystrophy (GCDII) is a rare form of stromal corneal dystrophy characterized by irregular-shaped well-demarcated granular deposits in the superficial central corneal stroma, and progressive visual impairment.
Uniprot Description A corneal disease resulting in reduced visual acuity and characterized by gray, crumb-like granular deposits in the anterior third of the stroma in each corneal button. Fusiform amyloid deposits, histochemically and morphologically identical to those of lattice corneal dystrophy, are found in the deeper stroma. Additional features include recurrent corneal erosions, and glare and decreased night vision.
Mondo Term and Equivalent IDs
MONDO:0011855:  granular corneal dystrophy type II
GARD:0009278: 
MESH:C535474: 
Orphanet:98963: 
SCTID:397568004: 
UMLS:C1275685: