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autosomal dominant Parkinson disease 4

Disease Summary
Associated Targets (1)
Tchem

1


Mondo Description A late onset Parkinson disease that has material basis in heterozygous triplication of the alpha-synuclein gene (SNCA) on chromosome 4q22.
Uniprot Description A complex neurodegenerative disorder with manifestations ranging from typical Parkinson disease to dementia with Lewy bodies. Clinical features include parkinsonian symptoms (resting tremor, rigidity, postural instability and bradykinesia), dementia, diffuse Lewy body pathology, autonomic dysfunction, hallucinations and paranoia.
Mondo Term and Equivalent IDs
MONDO:0011562:  autosomal dominant Parkinson disease 4
MESH:C565324: 
UMLS:C1854182: