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type 1 diabetes mellitus 12
Disease Summary
Associated Targets (1)
Tclin
1
Mondo Description Any type 1 diabetes mellitus in which the cause of the disease is a mutation in the CTLA4 gene.
Uniprot Description A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical features are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
Description from UniProt.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:0110751
MESH:C563326
OMIM:601388
UMLS:C1832392
MONDO:0011068
High level summary of knowledge for a disease, including descriptions and datasource references.