Mondo Description Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the CHMP2B gene.
Uniprot Description Characterized by an onset of dementia in the late 50's initially characterized by behavioral and personality changes including apathy, restlessness, disinhibition and hyperorality, progressing to stereotyped behaviors, non-fluent aphasia, mutism and dystonia, with a marked lack of insight. The brains of individuals with FTD3 have no distinctive neuropathological features. They show global cortical and central atrophy, but no beta-amyloid deposits.
Download Data for frontotemporal dementia and/or amyotrophic lateral sclerosis 7
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Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
Description from UniProt.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:0111227
MESH:C579991
OMIM:600795
SCTID:702393003
UMLS:C1833296
MONDO:0010936
High level summary of knowledge for a disease, including descriptions and datasource references.