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premature chromatid separation trait

Disease Summary
Associated Targets (1)
Tbio

1


Uniprot Description Consists of separate and splayed chromatids with discernible centromeres and involves all or most chromosomes of a metaphase. It is found in up to 2% of metaphases in cultured lymphocytes from approximately 40% of normal individuals. When PCS is present in 5% or more of cells, it is known as the heterozygous PCS trait and has no obvious phenotypic effect, although some have reported decreased fertility. Inheritance is autosomal dominant.
Mondo Term and Equivalent IDs
MONDO:0008304:  premature chromatid separation trait
EFO:0009077: 
UMLS:C1864389: