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type 1 diabetes mellitus 2
Disease Summary
Associated Targets (2)
Tbio
2
Mondo Description Any type 1 diabetes mellitus in which the cause of the disease is a mutation in the INS gene.
Uniprot Description A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical features are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.