Mondo Description Any microlissencephaly in which the cause of the disease is a mutation in the KATNB1 gene.

Uniprot Description A form of lissencephaly, a disorder of cortical development characterized by agyria or pachygyria and disorganization of the clear neuronal lamination of normal six-layered cortex. LIS6 features include hypoplasia of the corpus callosum, severe microcephaly and developmental delay.