Name Development Level Target Family
NAD-dependent protein deacetylase sirtuin-1 Tchem Epigenetic
Ornithine decarboxylase Tclin Enzyme
Multidrug and toxin extrusion protein 1 Tchem Transporter
Protein S100-B Tchem Non-IDG
Amiloride-sensitive amine oxidase [copper-containing] Tchem Enzyme
Name Description
suramin A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
DrugCentral Indication