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Download Data for IDG:D7096
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Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
High level summary of knowledge for a disease, including descriptions and datasource references.
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Opens the Target List with this set of targets
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Download Data for HIST1H1B
Description of the protein which includes the UniProt Function and the NCBI Gene Summary.
Uniprot linked accession values, symbols or commonly used abbreviations associated with this particular target.
Approved gene symbol with link to HUGO Gene Nomenclature Committee.
Ensembl identifier links.
List of abbreviations or acronyms of the full target name.
Radar plot depicting the variety of knowledge obtained by Pharos for a particular target. The more spikes in the plot, the more variety. The longer the length, the higher the quantity of that particular knowledge. Clicking the illumination graph opens an expanded view to explore the plot fuller by seeing plot with annotations of the different radii.
Table representing the top 5 knowledge attributes in the illumination graph. The knowledge value property is on a scale of 0 to 1.
Gene symbols, accession ids and various other target identifiers. Also contains the illumination graph which highlights the amount of knowledge available. Click the '?' button for more information
Hierarchical classifications for this protein from different ontologies.
Classes for this protein according to Protein ANalysis THrough Evolutionary Relationships (PANTHER) Classification System.
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Classes for this protein according to by Drug Target Ontology (DTO).
Explore targets in this DTO class
Descriptions of the IDG illumination levels, highlighting the milestones attained in research for this target.
Jensen Lab generated fractional counting score for the prevalence of this gene in Pubmed articles.
Total count of NCBI Gene Reference Into Function hits for target listed in parenthesis, and summary table with links to publications per PMID with the specific text in article that includes the reported target.
Number of antibodies for this target listed in antibodypedia.com
Number of Gene Ontology (GO) annotations for this target, consisting of the sum of GO Functions and GO Processes.
Ligands associated with a target, listed in ChEMBL, with activity over a cutoff relative to the targetclass.
Approved drugs associated with a target.
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Tap 'Apply' to filter the list to values that are >= 0.5 and <= 4.1
Filter the list to the current range
Tap 'Apply' to filter the list to values that are >= -2 and <= 7
Tap 'Apply' to filter the list to values that are >= 0.3 and <= 0.72
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Find targets based on amino acid sequence
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A classification of the degree to which proteins are studied or not studied, as evidenced by publications, tool compounds and other features.
See details for TBX21
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A note from the data source regarding the evidence behind the association between disease and target.
A measure from Monarch quantifying the association betweeen disease and target.
From DisGeNET, this measure quantifies the strength of evidence for the association between disease and target.
A note from DisGeNET or eRAM regarding the dataset which supplied the data.
A measure from the JensenLab data sources quantifying the confidence in the association between the disease and the target.
A measure from JensenLab Text Mining quantifying the strength of the association between the disease and the target.
Radar plot depicting the variety of knowledge obtained by Pharos for this target.
Gene Symbol
Primary UniProt accession number
A broad classification of protein families
Number of high confidence protein protein interactions for this target.
Jensen Lab generated fractional counting score for the prevalence of this target in PubMed articles.
A score based on text mining PubMed data.
Number of antibodies for this target listed in antibodypedia.com.
TIN-X metric for the relative scarcity of specific publications for this target.
See details for IL5
See details for IL1RL1
Based on data from Expression Atlas, this measure quantifies the change in expression between the disease and non-disease states which yielded this association between disease and target.
The significance of the association between disease and target based on the Expression Atlas log2foldchange.
See details for ORMDL3
See details for CCL2
See details for TNF
Explore Descendant Details
See details for TSLP
See details for ALOX5
See details for MUC7
See details for ADRB2