Severe major depression with psychotic features

Name	Development Level	Target Family
Histamine H1 receptor	Tclin	GPCR
Sodium-dependent noradrenaline transporter	Tclin	Transporter

Name	Description
doxepin	A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.

TCRDv4.6.0
DrugCentral Indication
DrugCentral
doxepin