Name Development Level Target Family
Muscarinic acetylcholine receptor M1 Tclin GPCR
Muscarinic acetylcholine receptor M2 Tclin GPCR
Muscarinic acetylcholine receptor M3 Tclin GPCR
Name Description
oxybutynin Oxybutynin acts as a competitive antagonist of acetylcholine at post-ganglionic muscarinic receptors, resulting in relaxation of bladder smooth muscle. Oxybutynin is a racemic (50:50) mixture of R- and S-isomers. Antimuscarinic activity resides predominantly in the R-isomer. The R-isomer of oxybutynin shows greater selectivity for the M1 and M3 muscarinic subtypes (predominant in bladder detrusor muscle and parotid gland) compared to the M2 subtype (predominant in cardiac tissue).
TCRDv4.6.0
DrugCentral Indication
DrugCentral
oxybutynin