Name Development Level Target Family
Neuronal acetylcholine receptor subunit alpha-7 Tchem Ion Channel
Glycine receptor subunit alpha-2 Tchem Ion Channel
Glycine receptor subunit alpha-3 Tchem Ion Channel
Name Description
ivermectin A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
DrugCentral Indication