Name Development Level Target Family
Cytochrome P450 11B1, mitochondrial Tclin Enzyme
Cholesterol side-chain cleavage enzyme, mitochondrial Tclin Enzyme
Name Description
mitotane A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
TCRDv4.6.0
DrugCentral Indication
DrugCentral
mitotane