Name Development Level Target Family
3-hydroxy-3-methylglutaryl-coenzyme A reductase Tclin Enzyme
Name Description
lovastatin A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
TCRDv4.6.0
DrugCentral Indication
DrugCentral
lovastatin