You are using an outdated browser. Please upgrade your browser to improve your experience.
experimental autoimmune encephalomyelitis
Disease Summary
Associated Targets (8)
Tbio
4
Tchem
3
Tclin
1
Mondo Description An autoimmune demyelinating disease of the central nervous system that is produced experimentally in animals by the injection of homogenized brain or spinal cord in Freund's adjuvant. Myelin basic protein appears to be the antigen that elicits the hypersensitivity immune response which is characterized by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Experimental allergic encephalomyelitis (EAE) is used as an animal model for demyelinating diseases of the human central nervous system such as multiple sclerosis.
Download Data for experimental autoimmune encephalomyelitis
data still loading...
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
EFO:0001066
MESH:D004681
MONDO:0005134
High level summary of knowledge for a disease, including descriptions and datasource references.