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type 2 diabetes mellitus
Disease Summary
Associated Targets (419)
Tbio
209
Tchem
105
Tclin
91
Tdark
14
Mondo Description A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.
Uniprot Description A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Disease Ontology Description A diabetes mellitus that involves high blood glucose resulting from cells fail to use insulin properly.
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
Description from UniProt.
Description from Disease Ontology
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
COHD:201826
DOID:9352
EFO:0001360
MESH:D003924
NCIT:C26747
OMIM:125853
SCTID:44054006
UMLS:CN244395
MONDO:0005148
High level summary of knowledge for a disease, including descriptions and datasource references.