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medullary thyroid gland carcinoma

Disease Summary
Associated Targets (19)
Tclin

11

Tchem

4

Tbio

4


GARD Rare
Mondo Description A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy.
Disease Ontology Description A follicular thyroid carcinoma that has_material_basis_in parafollicular cells.
Mondo Term and Equivalent IDs
MONDO:0015277:  medullary thyroid gland carcinoma
GARD:0007004: 
NCIT:C3879: 
ONCOTREE:THME: 
Orphanet:1332: 
SCTID:255032005: 
UMLS:C0206693: 
UMLS:C0238462: