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schistosomiasis

Disease Summary
Associated Targets (8)
Tchem

3

Tbio

3

Tclin

1

Tdark

1


GARD Rare
Mondo Description An infectious disease caused by parasitic trematodes of the genus Schistosoma that colonize human blood vessels and release eggs that can cause granulomatous reactions leading to acute (swimmer's itch or acute schistosomiasis syndrome) or chronic disease. Depending on where the eggs lodge, manifestations of chronic schistosomiasis can include diarrhea, abdominal pain, loss of appetite, anemia (intestines), hepatosplenism, periportal fibrosis with portal hypertension (liver), urogenital inflammation and scarring, hematuria and dysuria (genitourinary system). Other patients may be asymptomatic.
Disease Ontology Description A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria.
Mondo Term and Equivalent IDs
MONDO:0015254:  schistosomiasis
EFO:1001475: 
GARD:0009687: 
ICD9:120.9: 
MESH:D012552: 
NCIT:C35000: 
Orphanet:1247: 
SCTID:10087007: 
UMLS:C0036323: