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aplastic anemia

Disease Summary
Associated Targets (105)
Tbio

63

Tchem

26

Tclin

14

Tdark

2


Mondo Description Anemia resulting from bone marrow failure (aplastic or hypoplastic bone marrow). The production of erythroblasts and red cells is markedly decreased, and it may be associated with decreased production of granulocytes (granulocytopenia) and platelets (thrombocytopenia) as well. Aplastic anemia may be idiopathic or secondary due to bone marrow damage by toxins, radiation, or immunologic factors.
Uniprot Description A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. It is characterized by peripheral pancytopenia and marrow hypoplasia.
Disease Ontology Description An anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.
Mondo Term and Equivalent IDs
MONDO:0015909:  aplastic anemia
COHD:137829: 
ICD9:284.9: 
MESH:D000741: 
NCIT:C2870: 
Orphanet:182040: 
SCTID:306058006: