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acute hemorrhagic leukoencephalitis

Disease Summary
Associated Targets ()

Mondo Description Acute hemorrhagic leukoencephalitis(AHL) is a veryrareform of acute disseminated encephalomyelitis that usuallyresults indeath. It is characterized by a brief but intense attack of inflammation in the brain and spinal cord that damages the myelin -- the protective covering of the nerve fibers. It may also cause bleeding in the brain, leading to damage of the white matter. Symptoms usually come on quickly, beginning with symptoms such as fever, neck stiffness, fatigue, headache, nausea vomiting,seizures, and coma.AHL has a very poor prognosis, with rapid deterioration and death usually occurring within days to one week after onset of symptoms because of severe inflammation in the brain. Although the exact cause is unclear,AHL usually followsaviral infection, or less often, vaccination for measles, mumps, or rubella. Some researchers think that an infection or vaccination can initiate an autoimmune process in the body thus leading to AHL.
Mondo Term and Equivalent IDs
MONDO:0011716:  acute hemorrhagic leukoencephalitis
EFO:0007132: 
GARD:0008629: 
MESH:D004684: 
NCIT:C84535: 
SCTID:72986009: 
UMLS:C0014077: