Currently the diseases view is a work in progress and should not be considered a definitive resource yet

Development Level

Tbio 11,514
Tchem 5,369
Tclin 4,022
Tdark 2,033

Target Family

Non-IDG 9,589
Enzyme 6,369
Transcription Factor 2,695
Kinase 1,972
Transporter 1,621
Ion Channel 1,541
GPCR 1,532
Nuclear Receptor 811
Epigenetic 692
TF/Epigenetic 220
oGPCR 96

Drug

ciprofloxacin 86
prednisolone 68
lidocaine 16
progesterone 13
testosterone 11
heparin 10
itraconazole 10
vinblastine 8
hydroxychloroquine 8
alprostadil 7
diclofenac 7
phenylephrine 7
metoclopramide 6
benzocaine 6
ciclosporin 6
cilastatin 6
bevacizumab 6
cimetidine 6
theophylline 6
tretinoin 6
cortisone acetate 6
dexamethasone 6
ropivacaine 5
lamotrigine 5
paclitaxel 5
vincristine 5
dinoprostone 5
amantadine 5
diazepam 5
phentolamine 5
flavoxate 5
doxorubicin 5
liothyronine 5
allopurinol 5
pregabalin 4
beclometasone dipropionate 4
docetaxel 4
midazolam 4
imatinib 4
ezetimibe 4
citric acid 4
tacrolimus 4
aflibercept 4
promazine 4
aripiprazole 4
acetazolamide 4
naloxone 4
ziconotide 4
cetuximab 4
isoprenaline 4
dobutamine 4
spironolactone 4
pyrimethamine 4
asenapine 3
tetracosactide 3
bumetanide 3
trimetaphan 3
methotrexate 3
verapamil 3
amlodipine 3
meclozine 3
dipyridamole 3
dasatinib 3
mupirocin 3
nicotine 3
pentobarbital 3
lorazepam 3
flumazenil 3
chlordiazepoxide 3
lodoxamide 3
dicoumarol 3
zoledronic acid 3
ranitidine 3
famotidine 3
ibrutinib 3
epinephrine 3
niclosamide 3
losartan 3
ketoconazole 3
retinol 3
calcitriol 3
canakinumab 3
glycopyrronium bromide 3
hyoscyamine 3
naproxen 3
everolimus 3
clotrimazole 3
carmustine 3
tazarotene 3
edrophonium 3
glyceryl trinitrate 3
propranolol 3
hydroxycarbamide 3
pilocarpine 3
palifermin 3
pamidronic acid 2
norepinephrine 2
droperidol 2
prochlorperazine 2
clozapine 2

Data Source

TCRDv4.6.9 15,277
DisGeNET 6,981
Monarch 5,121
UniProt Disease 4,541
JensenLab Text Mining 3,592
DrugCentral Indication 1,226
DrugCentral 1,012
JensenLab Knowledge GHR 498
JensenLab Experiment DistiLD 206
Expression Atlas 141
JensenLab Knowledge UniProtKB-... 120
JensenLab Experiment COSMIC 63

DisGeNET Source

CTD_human 3,501
CLINVAR 2,796
ORPHANET 1,868
UNIPROT 1,804
GWASCAT 278
ID Name Description
DOID:1790 Malignant mesothelioma
DOID:5074 Posterior fossa group B ependymoma
DOID:2129 Atypical teratoid / rhabdoid tumor
DOID:0050902 Group 4 medulloblastoma
DOID:3857 Medulloblastoma, large-cell
DOID:12894 Non primary Sjogren syndrome sicca
DOID:5572 Beckwith-Wiedemann syndrome
DOID:11383 Cryptorchidism
MIM:249000 Meckel syndrome 1 A disorder characterized by a combination of renal cysts and variably associated features including developmental anomalies of the central nervous system (typically encephalocele), hepatic ductal dysplasia and cysts, and polydactyly.
MIM:615990 Bardet-Biedl syndrome 13 A syndrome characterized by usually severe pigmentary retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus) may be required for clinical manifestation of some forms of the disease.