Welcome to the GraphQL Playground for the Pharos. Queryable endpoints can be found on the DOCS tab on the right. Datatype definitions are on the SCHEMA tab.
Learn more about GraphQL: GraphQL.org
Given a gene symbol, this query fetches a number of simple details for the target.
query targetDetails{
target(q:{sym:"ACE2"}) {
name
tdl
fam
sym
description
novelty
}
}
Given a disease name, this query fetches some basic information about a disease, and one level of descendents, based on the Disease Ontology hierarchy
query diseaseDetails{
disease(name:"asthma"){
name
mondoDescription
uniprotDescription
doDescription
targetCounts {
name
value
}
children {
name
mondoDescription
}
}
}
Given a drug name, this query fetches some basic information about the drug and details of target activity measurements.
query ligandDetails{
ligand(ligid: "haloperidol") {
name
description
isdrug
synonyms {
name
value
}
smiles
activities {
target {
sym
}
type
value
}
}
}
Given a target symbol, this query fetches some basic details of the top 5 interacting proteins, and details of that interaction.
query interactingProteins{
targets(filter: { associatedTarget: "CAMKK1" }) {
targets(top:5) {
name
sym
ppiTargetInteractionDetails {
dataSources:ppitypes
score
interaction_type
evidence
p_ni
p_int
p_wrong
}
}
}
}
There are two queries given here. Given a disease name, the first query fetches the top 5 associated targets, and details of that association. Given a target symbol, the second query fetches associated diseasese. (You may need to click 'prettify' to execute both queries)
query associatedTargets{
targets(filter: { associatedDisease: "asthma" }) {
targets(top: 5) {
name
sym
diseaseAssociationDetails {
name
dataType
evidence
}
}
}
}
query associatedDiseases{
diseases(filter:{associatedTarget:"ORMDL3"}){
diseases{
name
}
}
}
Fetches the default facets for all targets in TCRD.
query facetsForAllTargets {
targets {
facets {
facet
values {
name
value
}
}
}
}
Fetches the default facets for all targets associated with a given disease.
query facetsForTargetsForDisease {
targets(filter: { associatedDisease: "asthma" }) {
facets {
facet
dataType
values {
name
value
}
}
}
}
Fetching the default facets, filtering by facet values. Note facets only filter the target list as it applies to the other facets, not themselves.
query filteringByFacets {
targets(
filter: {
facets: [{
facet: "Target Development Level",
values: ["Tclin", "Tchem"]
}]
}
) {
facets {
facet
values {
name
value
}
}
}
}
Uncommon facets can be fetched thusly.
query fetchingUncommonFacets {
targets(facets:["Ortholog"]) {
facets {
facet
values {
name
value
}
}
}
}
All facets that are currently supported in a target list.
query getAllTargetFacets {
targetFacets
}