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vitiligo

Disease Summary
Associated Targets (322)
Tbio

232

Tchem

45

Tdark

30

Tclin

15


Explore Associated Targets
Mondo Description Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes.
Uniprot Description A pigmentary disorder of the skin and mucous membranes. It is characterized by circumscribed depigmented macules and patches, commonly on extensor aspects of extremities, on the face or neck and in skin folds. Vitiligo is a progressive disorder in which some or all of the melanocytes in the affected skin are selectively destroyed. It is a multifactorial disorder with a complex etiology probably including autoimmune mechanisms, and is associated with an elevated risk of other autoimmune diseases.
Disease Ontology Description An autoimmune hypersensitivity disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.
Mondo Term and Equivalent IDs
MONDO:0008661:  vitiligo
COHD:138502: 
DOID:12306: vitiligo
EFO:0004208: 
ICD10:L80: 
MESH:D014820: 
NCIT:C26915: 
UMLS:C0042900: 
GWAS Targets (2372)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tclin
3
3
0
1.3
97.6
Tchem
3
3
0
1.3
97.6
Tbio
3
3
0
1.3
97.6
Tbio
3
3
0
1.3
97.6
Tbio
3
3
0
1.3
97.6
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tclin
0
1.3
97.6
Tchem
0
1.3
97.6
Tbio
0
1.3
97.6
Tbio
0
1.3
97.6
Tbio
0
1.3
97.6
Target Novelty (Tin-x)