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visceral leishmaniasis

Disease Summary
Associated Targets (27)
Tbio

14

Tdark

6

Tclin

4

Tchem

3


Mondo Description A severe form of leishmaniasis characterized by irregular bouts of fever, substantial weight loss, swelling of the spleen and liver, and anaemia (which may be serious). If left untreated it may lead to death. Two species of Leishmania are known to give rise to the visceral form of the disease. The species commonly found in East Africa and the Indian subcontinent is L. donovani and the species found in Europe, North Africa, and Latin America is L. infantum, also known as L. chagasi.
Disease Ontology Description A leishmaniasis that is the most severe form of the disease caused by protozoan parasites of the Leishmania genus, resulting in the infection of the internal organs such as liver, spleen and bone marrow. The symptoms include fever, weight loss, and an enlarged spleen and liver.
Mondo Term and Equivalent IDs
MONDO:0005445:  visceral leishmaniasis
COHD:200652: 
EFO:0005045: 
ICD10:B55.0: 
ICD9:085.0: 
MESH:D007898: 
NCIT:C34771: 
OMIMPS:608207: 
SCTID:186803007: 
UMLS:C0023290: