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vasculitis

Disease Summary
Associated Targets (286)
Tbio

189

Tchem

51

Tclin

30

Tdark

16


Mondo Description Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. BehC'et disease) to relatively minor skin disease.
Disease Ontology Description A vascular disease that is characterized by inflammation of the blood vessels.
Mondo Term and Equivalent IDs
MONDO:0018882:  vasculitis
EFO:0006803: 
GARD:0009565: 
MESH:D014657: 
NCIT:C26912: 
Orphanet:52759: 
SCTID:31996006: 
UMLS:C0042384: