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undifferentiated high grade pleomorphic sarcoma of bone
Disease Summary
Associated Targets ()
Mondo Description A rare, high-grade pleomorphic malignant neoplasm arising from the bone. It usually presents with pain which may or may not be associated with swelling in the affected area. It is characterized by the presence of spindle-shaped cells, polygonal or epithelioid cells, multinucleated giant cells, and inflammatory cells. The neoplastic cells exhibit nuclear pleomorphism and high mitotic activity. It metastasizes frequently, most often in the lungs.
Mondo Term and Equivalent IDs
MONDO:0002618: undifferentiated high grade pleomorphic sarcoma of bone
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Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:3352
NCIT:C8563
UMLS:C0740479
MONDO:0002618
High level summary of knowledge for a disease, including descriptions and datasource references.