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type 2 diabetes mellitus

Disease Summary
Associated Targets (2446)
Tbio

1587

Tdark

391

Tchem

309

Tclin

159


Explore Associated Targets
Mondo Description A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.
Uniprot Description A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Disease Ontology Description A diabetes mellitus that involves high blood glucose resulting from cells fail to use insulin properly.
Mondo Term and Equivalent IDs
MONDO:0005148:  type 2 diabetes mellitus
COHD:201826: 
EFO:0001360: 
MESH:D003924: 
NCIT:C26747: 
SCTID:44054006: 
UMLS:CN244395: 
GWAS Targets (3134)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
41
13
7
1.4
99.9
Tclin
24
14
7
1.3
99.8
Tbio
23
14
3
1.2
99.8
Tbio
25
14
5
1.1
99.7
Tbio
22
8
6
1.3
99.6
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
7
1.4
99.9
Tclin
7
1.3
99.8
Tbio
3
1.2
99.8
Tbio
5
1.1
99.7
Tbio
6
1.3
99.6
Target Novelty (Tin-x)
Too many associated targets