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tauopathy

Disease Summary
Associated Targets (738)
Tbio

486

Tchem

108

Tdark

100

Tclin

44


Mondo Description Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (tau proteins) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with alzheimer disease; dementia; parkinsonian disorders; progressive supranuclear palsy (supranuclear palsy, progressive); and corticobasal degeneration.
Disease Ontology Description A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.
Mondo Term and Equivalent IDs
MONDO:0005574:  tauopathy
EFO:0005815: 
MESH:D024801: 
UMLS:C0949664: 
Target Novelty (Tin-x)