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squamous cell carcinoma

Disease Summary
Associated Targets (350)
Tbio

206

Tchem

98

Tclin

44

Tdark

2


Disease Ontology Description A carcinoma that derives_from squamous epithelial cells.
DataSource References
DisGeNET: C0007137
CTD: DOID:1749
Monarch: DOID:1749
JensenLab Text Mining: DOID:1749
DrugCentral Indication: DOID:1749
eRAM: DOID:1749
GWAS Targets (108)
Items per page:
1 – 5 of 108
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Serine/threonine-protein kinase Chk2 (CHEK2)
Tchem
2
2
0
1.7
96.8
Differentially expressed in FDCP 8 homolog (DEF8)
Tdark
2
2
0
1.3
96.5
Breast cancer type 2 susceptibility protein (BRCA2)
Tbio
2
2
0
1.8
95.7
Membrane-associated transporter protein (SLC45A2)
Tbio
2
2
0
1.8
92.4
Interferon regulatory factor 4 (IRF4)
Tbio
2
1
0
1.6
92.2
Items per page:
1 – 5 of 108
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Serine/threonine-protein kinase Chk2 (CHEK2)
Tchem
0
1.7
96.8
Differentially expressed in FDCP 8 homolog (DEF8)
Tdark
0
1.3
96.5
Breast cancer type 2 susceptibility protein (BRCA2)
Tbio
0
1.8
95.7
Membrane-associated transporter protein (SLC45A2)
Tbio
0
1.8
92.4
Interferon regulatory factor 4 (IRF4)
Tbio
0
1.6
92.2
Disease Hierarchy
Parents
carcinoma (15219)
Tbio

10010

Tdark

3143

Tchem

1469

Tclin

597

Children
spindle cell carcinoma (163)
Tbio

96

Tchem

47

Tclin

19

Tdark

1

esophagus squamous cell carcinoma (82)
Tbio

52

Tchem

19

Tclin

10

Tdark

1

head and neck squamous cell carcinoma (29)
Tbio

17

Tchem

9

Tclin

3

malignant pleural mesothelioma (7)
Tchem

4

Tclin

3

laryngeal squamous cell carcinoma (4)
Tbio

2

Tclin

1

Tchem

1

lung squamous cell carcinoma (1)
Tclin

1

adenoid squamous cell carcinoma (0)
adenosquamous bile duct carcinoma (0)
adenosquamous breast carcinoma (0)
adenosquamous carcinoma (0)
adenosquamous colon carcinoma (0)
adenosquamous gallbladder carcinoma (0)
adenosquamous lung carcinoma (0)
adenosquamous prostate carcinoma (0)
ampulla of Vater adenosquamous carcinoma (0)
ampulla of Vater squamous cell carcinoma (0)
anal canal squamous cell carcinoma (0)
anal margin squamous cell carcinoma (0)
anal squamous cell carcinoma (0)
Bartholin's gland squamous cell carcinoma (0)
basaloid squamous cell carcinoma (0)
basaloid squamous cell skin carcinoma (0)
bladder squamous cell carcinoma (0)
bladder urachal squamous cell carcinoma (0)
bone squamous cell carcinoma (0)
breast squamous cell carcinoma (0)
cervical adenosquamous carcinoma (0)
cervical squamous cell carcinoma (0)
colon squamous cell carcinoma (0)
conjunctival squamous cell carcinoma (0)
cornea squamous cell carcinoma (0)
endometrial adenosquamous carcinoma (0)
endometrial squamous cell carcinoma (0)
esophageal adenosquamous carcinoma (0)
esophageal basaloid squamous cell carcinoma (0)
ethmoid sinus squamous cell carcinoma (0)
external ear squamous cell carcinoma (0)
fallopian tube squamous cell carcinoma (0)
frontal sinus squamous cell carcinoma (0)
gallbladder squamous cell carcinoma (0)
gastric adenosquamous carcinoma (0)
gastric squamous cell carcinoma (0)
glottis squamous cell carcinoma (0)
keratinizing squamous cell carcinoma (0)
lacrimal gland squamous cell carcinoma (0)
maxillary sinus squamous cell carcinoma (0)
middle ear squamous cell carcinoma (0)
nasal cavity squamous cell carcinoma (0)
oral squamous cell carcinoma (0)
ovarian squamous cell carcinoma (0)
pancreatic adenosquamous carcinoma (0)
pancreatic squamous cell carcinoma (0)
papillary squamous carcinoma (0)
penis squamous cell carcinoma (0)
peritoneal mesothelioma (0)
pharynx squamous cell carcinoma (0)
prostate squamous cell carcinoma (0)
rectum squamous cell carcinoma (0)
renal pelvis squamous cell carcinoma (0)
scrotum squamous cell carcinoma (0)
skin squamous cell carcinoma (0)
sphenoid sinus squamous cell carcinoma (0)
squamous cell bile duct carcinoma (0)
subglottis squamous cell carcinoma (0)
supraglottis squamous cell carcinoma (0)
thymus adenosquamous carcinoma (0)
thymus squamous cell carcinoma (0)
tonsil squamous cell carcinoma (0)
trachea squamous cell carcinoma (0)
ureter squamous cell carcinoma (0)
urethra squamous cell carcinoma (0)
verrucous carcinoma (0)
vulva squamous cell carcinoma (0)
Target Novelty (Tin-x)