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schizophrenia

Disease Summary
Associated Targets (2268)
Tbio

1463

Tchem

346

Tdark

265

Tclin

194


Explore Associated Targets
Mondo Description A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.
Uniprot Description A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder.
Disease Ontology Description A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.
Mondo Term and Equivalent IDs
MONDO:0005090:  schizophrenia
EFO:0000692: 
ICD9:295.90: 
NCIT:C3362: 
SCTID:58214004: 
GWAS Targets (2609)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tdark
4
6
0
1.2
97.1
Tdark
4
6
0
1.2
97.1
Tdark
4
6
0
1.2
97.1
Tdark
4
6
0
1.2
97.1
Tdark
4
6
0
1.2
97.1
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tdark
0
1.2
97.1
Tdark
0
1.2
97.1
Tdark
0
1.2
97.1
Tdark
0
1.2
97.1
Tdark
0
1.2
97.1
Disease Hierarchy
Target Novelty (Tin-x)
Too many associated targets