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rheumatoid arthritis

Disease Summary
Associated Targets (1510)
Tbio

1046

Tchem

241

Tdark

140

Tclin

83


Explore Associated Targets
Mondo Description A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.
Uniprot Description An inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
Disease Ontology Description An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.
Mondo Term and Equivalent IDs
MONDO:0008383:  rheumatoid arthritis
COHD:80809: 
EFO:0000685: 
ICD9:714.0: 
MESH:D001172: 
NCIT:C2884: 
SCTID:69896004: 
UMLS:C0003873: 
GWAS Targets (1019)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
15
13
18
2.2
99.8
Tbio
15
13
12
2.2
99.8
Tbio
15
13
6
2.2
99.8
Tbio
15
13
12
2.2
99.8
Tbio
15
13
6
2.2
99.8
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
18
2.2
99.8
Tbio
12
2.2
99.8
Tbio
6
2.2
99.8
Tbio
12
2.2
99.8
Tbio
6
2.2
99.8
Target Novelty (Tin-x)