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pulmonary fibrosis

Disease Summary
Associated Targets (205)
Tbio

103

Tchem

63

Tclin

21

Tdark

18


Mondo Description Chronic progressive interstitial lung disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure, or right heart failure. Causes include chronic inflammatory processes, exposure to environmental irritants, radiation therapy, autoimmune disorders, certain drugs, or it may be idiopathic (no identifiable cause).
Disease Ontology Description An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
Mondo Term and Equivalent IDs
MONDO:0002771:  pulmonary fibrosis
MESH:D011658: 
NCIT:C26869: 
SCTID:51615001: 
UMLS:C0034069: