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prion disease
Disease Summary
Associated Targets (44)
Tbio
27
Tchem
7
Tdark
6
Tclin
4
Mondo Description A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.
Disease Ontology Description A brain disease that is characterized by brain damage resulting from the abnormal folding, clumping and accumulation of cellular proteins in the brain induced by prion proteins.
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
Description from Disease Ontology
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:649
EFO:0004720
MESH:D017096
NCIT:C128346
SCTID:230284004
MONDO:0005429
High level summary of knowledge for a disease, including descriptions and datasource references.