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primary angle-closure glaucoma

Disease Summary
Associated Targets (22)
Tbio

15

Tdark

4

Tchem

3


Explore Associated Targets
Mondo Description An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.
Mondo Term and Equivalent IDs
MONDO:0001868:  primary angle-closure glaucoma
COHD:435543: 
EFO:1001506: 
ICD10:H40.2: 
ICD9:365.20: 
SCTID:392288006: 
UMLS:C0017606: 
GWAS Targets (22)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
1
1
0
1.2
75.9
Tbio
1
1
0
1.2
70.9
Tchem
1
1
0
1.2
70.9
Tbio
1
1
0
1.2
70.9
Tbio
1
1
0
1.2
66.3
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
1.2
75.9
Tbio
0
1.2
70.9
Tchem
0
1.2
70.9
Tbio
0
1.2
70.9
Tbio
0
1.2
66.3
Target Novelty (Tin-x)