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paraneoplastic syndrome

Disease Summary
Associated Targets (50)
Tclin

42

Tchem

5

Tbio

3


Explore Associated Targets
Mondo Description A classification for rare disorders of diverse organ systems (endocrine, neuromuscular, gastrointestinal, renal, dermatologic, rheumatologic, hematologic) that are affected by substances secreted by a distant neoplasm but not by the action of the neoplasm itself metastasizing to that organ or tissue. Less than 1 % of neoplasms are associated with these syndromes. An immune-mediated response to neoplasm-elaborated proteins may be the cause of these syndromes. Additionally, their manifestation may signal the presence of an occult neoplasm, potentially at an earlier stage of disease thereby leading to a better clinical outcome. Constitutional signs may include fever, night sweats, anorexia and cachexia. Clinical course is usually progressive. Prognosis is variable depending on the effective treatment of the underlying neoplasm.
Mondo Term and Equivalent IDs
MONDO:0021073:  paraneoplastic syndrome
MESH:D010257: 
NCIT:C3311: 
SCTID:49783001: 
UMLS:C0030472: 
GWAS Targets (0)
No GWAS traits found
Target Novelty (Tin-x)
No novelty measurements found