You are using an outdated browser. Please upgrade your browser to improve your experience.

ovarian carcinoma

Disease Summary
Associated Targets (247)
Tbio

141

Tchem

57

Tdark

29

Tclin

20


Explore Associated Targets
Mondo Description A malignant neoplasm originating from the surface ovarian epithelium. It accounts for the greatest number of deaths from malignancies of the female genital tract and is the fifth leading cause of cancer fatalities in women. It is predominantly a disease of older white women of northern European extraction, but it is seen in all ages and ethnic groups. Adenocarcinomas constitute the vast majority of ovarian carcinomas. The pattern of metastatic spread in ovarian carcinoma is similar regardless of the microscopic type. The most common sites of involvement are the contralateral ovary, peritoneal cavity, para-aortic and pelvic lymph nodes, and liver. Lung and pleura are the most common sites of extra-abdominal spread. The primary form of therapy is surgical. The overall prognosis of ovarian carcinoma remains poor, a direct result of its rapid growth rate and the lack of early symptoms. --2002
Disease Ontology Description An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.
Mondo Term and Equivalent IDs
MONDO:0005140:  ovarian carcinoma
EFO:0001075: 
NCIT:C4908: 
GWAS Targets (161)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
3
2
0
1.5
88.3
Tbio
7
2
0
1.3
85.7
Tbio
3
2
0
1.1
83.4
Tbio
3
2
0
1.1
83.4
Tdark
3
2
0
1.1
83.4
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
1.5
88.3
Tbio
0
1.3
85.7
Tbio
0
1.1
83.4
Tbio
0
1.1
83.4
Tdark
0
1.1
83.4
Target Novelty (Tin-x)