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neuromyelitis optica

Disease Summary
Associated Targets (30)
Tbio

24

Tclin

4

Tchem

2


Explore Associated Targets
Mondo Description Neuromyelitis optica (NMO) and NMO spectrum disorders are inflammatory demyelinating diseases of the central nervous system characterized mainly by attacks of uni- or bilateral optic neuritis (ON) and acute myelitis.
Disease Ontology Description A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis).
Mondo Term and Equivalent IDs
MONDO:0019100:  neuromyelitis optica
COHD:380995: 
DOID:8869: neuromyelitis optica
EFO:0004256: 
GARD:0006267: 
ICD9:341.0: 
MESH:D009471: 
NCIT:C84934: 
Orphanet:71211: 
SCTID:25044007: 
UMLS:C0027873: 
GWAS Targets (127)
Items per page:
1 – 5 of 127
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HLA class II histocompatibility antigen, DRB1-11 beta chain (HLA-DRB1)
Tbio
2
2
0
2.4
53.7
HLA class II histocompatibility antigen, DRB1-4 beta chain (HLA-DRB1)
Tbio
2
2
0
2.4
53.7
HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1)
Tbio
2
2
0
2.4
53.7
HLA class II histocompatibility antigen, DRB1-4 beta chain (HLA-DRB1)
Tbio
2
2
0
2.4
53.7
HLA class II histocompatibility antigen, DRB1-15 beta chain (HLA-DRB1)
Tchem
2
2
0
2.4
53.7
Items per page:
1 – 5 of 127
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HLA class II histocompatibility antigen, DRB1-11 beta chain (HLA-DRB1)
Tbio
0
2.4
53.7
HLA class II histocompatibility antigen, DRB1-4 beta chain (HLA-DRB1)
Tbio
0
2.4
53.7
HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1)
Tbio
0
2.4
53.7
HLA class II histocompatibility antigen, DRB1-4 beta chain (HLA-DRB1)
Tbio
0
2.4
53.7
HLA class II histocompatibility antigen, DRB1-15 beta chain (HLA-DRB1)
Tchem
0
2.4
53.7
Target Novelty (Tin-x)