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myeloproliferative neoplasm

Disease Summary
Associated Targets (1078)
Tbio

685

Tchem

195

Tdark

107

Tclin

91


Explore Associated Targets
Mondo Description A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)
Disease Ontology Description A myeloid neoplasm that is characterized by a group of slow growing blood cancers in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood.
Mondo Term and Equivalent IDs
MONDO:0020076:  myeloproliferative neoplasm
EFO:0002428: 
EFO:0004251: 
GARD:0009319: 
NCIT:C4345: 
ONCOTREE:MPN: 
Orphanet:98274: 
SCTID:425333006: 
UMLS:C1292778: 
GWAS Targets (31)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tclin
3
3
0
2
97.7
Tdark
3
3
0
2
97.7
Tbio
1
2
0
1.5
93.2
Tchem
1
2
0
1.5
93.2
Tchem
1
2
0
1.5
93.2
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tclin
0
2
97.7
Tdark
0
2
97.7
Tbio
0
1.5
93.2
Tchem
0
1.5
93.2
Tchem
0
1.5
93.2
Disease Hierarchy
Target Novelty (Tin-x)