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malaria

Disease Summary
Associated Targets (78)
Tbio

39

Tdark

19

Tchem

11

Tclin

9


Explore Associated Targets
Mondo Description Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly.Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
Disease Ontology Description A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
Mondo Term and Equivalent IDs
MONDO:0005136:  malaria
COHD:438067: 
DOID:12365: malaria
EFO:0001068: 
GARD:0006961: 
ICD10:B53: 
MESH:D008288: 
NCIT:C34797: 
Orphanet:673: 
SCTID:61462000: 
UMLS:C0024530: 
GWAS Targets (45)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
2
2
0
1.4
85.5
Tbio
2
2
0
1.4
85.5
Tbio
2
2
0
1.4
85.5
Tbio
2
2
0
1.4
85.5
Tbio
2
2
0
1.4
85.5
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
1.4
85.5
Tbio
0
1.4
85.5
Tbio
0
1.4
85.5
Tbio
0
1.4
85.5
Tbio
0
1.4
85.5
Disease Hierarchy
Target Novelty (Tin-x)