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leukemia

Disease Summary
Associated Targets (1721)
Tbio

1115

Tchem

311

Tdark

158

Tclin

137


Mondo Description A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.
Disease Ontology Description A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.
Mondo Term and Equivalent IDs
MONDO:0005059:  leukemia
EFO:0000565: 
ICD9:208.90: 
MESH:D007938: 
NCIT:C3161: 
SCTID:93143009: 
UMLS:C0023418: 
Disease Hierarchy
Target Novelty (Tin-x)