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juvenile idiopathic arthritis

Disease Summary
Associated Targets (328)
Tbio

223

Tchem

56

Tclin

29

Tdark

20


Mondo Description Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases).
Uniprot Description An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
Disease Ontology Description A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint.
Mondo Term and Equivalent IDs
MONDO:0011429:  juvenile idiopathic arthritis
COHD:75622: 
MESH:D001171: 
NCIT:C114357: 
Orphanet:92: 
SCTID:410502007: