You are using an outdated browser. Please upgrade your browser to improve your experience.

inflammatory bowel disease 19

Disease Summary
Associated Targets (1)


Uniprot Description A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.
DataSource References
DisGeNET: C2677079
CTD: MESH:C567372
UniProt Disease: MIM:612278
Monarch: OMIM:612278