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immunodeficiency due to a late component of complement deficiency

Disease Summary
Associated Targets (6)
Tbio

4

Tclin

1

Tchem

1


Mondo Description A genetic deficiency of any membrane attack complex (MAC, also known as terminal component complex (TCC)) component of the complement system (C5, C6, C7, C8, C9). Deficiencies of the terminal complement pathway results in a predisposition to infections, such as invasive meningococcal disease or disseminated gonococcal infection.
Mondo Term and Equivalent IDs
MONDO:0015700:  immunodeficiency due to a late component of complement deficiency
Orphanet:169150: